Last Updated: October 25, 2022.
For the latest CDC information on travel to Tanzania, including Zanzibar, please review the CDC's information directly.
Make sure you are up-to-date on routine vaccines before every trip. These vaccines include measles-mumps-rubella (MMR) vaccine, diphtheria-tetanus-pertussis vaccine, varicella (chickenpox) vaccine, polio vaccine, and your yearly flu shot.
CDC recommends this vaccine because you can get hepatitis A through contaminated food or water in Tanzania, regardless of where you are eating or staying.
You can get hepatitis B through sexual contact, contaminated needles, and blood products, so CDC recommends this vaccine if you might have sex with a new partner, get a tattoo or piercing, or have any medical procedures.
Vaccination may be considered for adults who are traveling to areas of active cholera transmission. Areas of active cholera transmission are localized to the regions of Arusha (last case reported April 2019), Dar es Salaam (last case reported July 2019), Songwe (last case reported March 2019), and Tanga (last case reported July 2019) in Tanzania. Cholera is rare in travelers but can be severe. Certain factors may increase the risk of getting cholera or having severe disease. Avoiding unsafe food and water and washing your hands can also help prevent cholera.
You can get typhoid through contaminated food or water in Tanzania. CDC recommends this vaccine for most travelers, especially if you are staying with friends or relatives, visiting smaller cities or rural areas, or if you are an adventurous eater.
Rabies can be found in dogs, bats, and other mammals in Tanzania, so CDC recommends this vaccine for the following groups:
Required if traveling from a country with risk of YF virus transmission and ≥1 year of age, including transit >12 hours in an airport located in a country with risk of YF virus transmission.1 Generally not recommended for travelers to Tanzania. Note: Yellow fever vaccine availability in the United States is currently limited.
*Additional Vaccinations may be recommended based on traveler’s medical history
Atovaquone-Proguanil(Malarone), Doxycycline, Mefloquine, or Tafenoquine. Chloroquine not recommended secondary to drug resistance.
Because dengue is spread by mosquito bites, all travelers to risk areas should prevent mosquito bites by using an EPA-registered insect repellent, wearing long-sleeved shirts and long pants when outdoors, and sleeping in an air-conditioned room or room with window screens or under an insecticide-treated bed net.